Why bioinformatics and proteomic application essential in the Annotated Bibliography

Why bioinformatics and proteomic application essential in the diagnosis of complex disease such as cancer - Annotated Bibliography Example However, the article’s limitation is that it does not clearly distinguish the number of females and males plus kids in the study. Martin, J., Regad, L., Etchebest, C., & Camproux, A. (2008). Taking advantage of local structure descriptors to analyze interresidue contacts in protein structures and protein complexes. Proteins: Structure, Function, and Bioinformatics, 73(3), 672-689. 3-Duh, Q. (2004) It is noteworthy that the article first describes cancer as caused by the alteration of not only the proteome, but also a genome. These changes inculcate the ability to evade normal cellular control mechanism on cancer cells hence prompting its uncontrolled growth. The article further demonstrates that prior to the efforts of scientists; cancer is controllable to some extent, or even totally if detected at its early stages. Considerably, among the several individuals who were interviewed on the same, are concluded to be ignorant. It emerged that the respondents sought the medical attention upon developing the symptoms of the disorder. However, the limitation of the article is that it does not illustrate perfectly the reason to why patients usually seek medical help at a later stage of cancer. The importance of bioinformatics in cancer disease is highlighted in this article. Bioinformatics is the study of predictive molecular signatures also called biomarkers. Biomarkers are a form of molecules whose occurrence indicates the pedigree of several diseases. This is a point where the scientists started to explore in their quest to find a limiting factor to this terrible disease. It is imperative that the author of this article did not highlight on the details of the biomarkers, thus, the arguments are limited. The author alludes that the biomarkers have been discovered to limit the severity of the disease in human body. The above article states that, since the growth of cancer portrays a form of multi-scale process, which is dominated by an invariable that exudes

Investigate and asses the lives and work of the two Caribbean Essay

Investigate and asses the lives and work of the two Caribbean personalities who, in your opinion, made the greatest contribution to the development of thier own - Essay Example In 1975 he won this countrys lone medal Silver in the 100 metres at the Pan American Games in Mexico City, Mexico. The following year history was created when he won Trinidad and Tobagos first Gold Medal in the 100 metres at the 1976 Olympic Games in Montreal, Canada. [Regis, 1999] In 1975, Crawford was added to the team of American coach Bob Parks, who prepared Crawford excellently for the 100 m and 200 m events at the Montreal Olympics, running only a few races during the season. The tactics paid off, as Crawford won the 100 m, narrowly in front of Don Quarrie of Jamaica, winning Trinidad and Tobagos first Olympic gold medal. He had also qualified for the 200 m final, but pulled out due to an injury. Hasely Crawford ´s last success was a bronze medal in the 1978 Commonwealth Games (100 m). He did also participate in the 1980 and 1984 Olympics, the most participations for an Olympian of Trinidad and Tobago but didnt reach to a final again. In the year 2000 he was named the Trinidad & Tobago Athlete of the Millennium.Crawford is a national hero in his home country, Crawford has appeared on postage stamps and has an airplane and a sports stadium named after him. Hasely Crawford’s remarkable achievement are not only restricted to his sports field but also as a person who contributed a lot to his society and people through his social work. His social work as the Head Community Relation at National Gas Company at Trinidad and Tobago is outstanding. He has done a great job in maintaining relationships from different institutions and invested a great deal to enhance the cohesive work environment. [Bow on World Stage Can Put Marvin with His Nations Greats, 2006] Crawford was specially invited to attend the Athens Games by the World Olympians Association, a body of which he is the Trinidad and Tobago president. Crawford’s contribution as an athlete is quite worthy in a sense that Trinidad and Tobago Olympic Committee appointed him as